As you know, the deep tech venture capital landscape has exploded this year, but who are the top players in deep tech VC?
The sector is attracting unprecedented investment as transformative technologies reshape entire industries.
From artificial intelligence and quantum computing to biotechnology and advanced robotics, deep tech represents the cutting edge of innovation, and the investors funding these breakthroughs are becoming household names in the startup ecosystem.
Understanding who the top players are can help founders identify the right partners for their groundbreaking ventures.
Who Are The Top Players in Deep Tech VC
Deep tech is no longer a niche category.
In 2025 through September, deep tech companies raised $139 billion in equity funding across 1,970 rounds, representing a remarkable 128% increase compared to the same period in 2024.
The deep tech market is projected to reach $714.6 billion by 2031, growing at an impressive compound annual growth rate of 48.2%.
What makes deep tech investing unique is the long development cycles, significant R&D requirements, and specialized expertise needed to evaluate opportunities.
The top VC firms in this space understand these dynamics and bring not just funding, but strategic value to their portfolio companies.
The Elite Deep Tech VC Firms
| Firm | Focus Areas | Notable Investments | Investment Stage |
|---|---|---|---|
| Lux Capital | AI, biotech, robotics, space tech | Anduril, Zoox, Heliogen | Seed to Series A |
| DCVC | AI, machine learning, computational science | Planet Labs, Recursion, Benchling | Series A+ |
| SOSV | Biotech, food tech, robotics, hardware | IndieBio & HAX portfolio companies | Pre-seed to Seed |
| Andreessen Horowitz | AI, robotics, healthcare, life sciences | Oculus VR, Cloudera, OpenAI | Seed to Growth |
| Khosla Ventures | Energy, space, materials, agtech, biotech | Climate tech and biotech leaders | Seed to Series B |
| Two Sigma Ventures | Computer vision, ML, AI, data science | 3DR, Anomalo, Enigma | Seed to Series A+ |
| Boost VC | Aerospace, VR/AR, crypto, bio, AI/ML | Coinbase, Starfish Space, K2 Space | Pre-seed |
1. Lux Capital

Lux Capital has built its reputation on making risky bets where technology intersects with world-changing ideas, focusing heavily on AI, robotics, biotech, and space tech.
With over 20 years of experience and $5 billion in assets under management, Lux doesn’t just fund companies; they champion technologies that others might consider too ambitious or too far from commercialization.
2. DCVC

DCVC specializes in funding data-driven enterprises tackling hard science innovation, with particular expertise in artificial intelligence, machine learning, and computational science.
Their portfolio reads like a who’s who of companies using advanced technology to solve fundamental problems in industries ranging from agriculture to pharmaceuticals.
3. SOSV

SOSV provides not just funding but a strong mentorship ecosystem for hard tech founders through programs like IndieBio and HAX, focusing on biotech, food tech, robotics, and hardware.
Managing over $1.5 billion in assets with a focus on deep tech and planetary health investments, SOSV has become synonymous with early-stage deep tech acceleration.
4. The Generalist Powerhouses

While specialized deep tech firms have carved out impressive niches, generalist giants like Andreessen Horowitz (a16z) and Sequoia Capital continue to deploy significant capital into deep tech opportunities.
A16z has been particularly active in deep tech, launching a $200 million fund exclusively for AI investments in 2016 and a $450 million fund for healthcare and life sciences in 2018.
Their portfolio includes groundbreaking companies like Oculus VR and OpenAI.
Investment Trends Shaping Deep Tech
| Sector | 2025 Investment Highlights | Key Drivers |
|---|---|---|
| AI & Machine Learning | 51% of all VC funding; $89.4B raised by AI startups | Generative AI, enterprise applications, automation |
| Quantum Computing | $1B+ mega-rounds (PsiQuantum, Quantinuum) | Breakthrough computational capabilities, defense applications |
| Space Tech | $6B in 2024; continued momentum in 2025 | Satellite manufacturing, space-based solar power, and microgravity |
| Biotech & Life Sciences | Record Series A rounds; gene therapy advancement | Precision medicine, RNA therapeutics, protein sequencing |
| Robotics & Hardware | Growing focus on industrial automation & defense | Labor shortages, supply chain resilience, AI integration |
Sector-Specific Deep Tech Investors
Beyond broad-based deep tech firms, sector-specific investors have emerged as powerful players in their respective domains.
Konvoy

Konvoy, a leading example of sector-focused deep tech investing, exclusively targets the video gaming ecosystem where innovations like AI, advanced graphics rendering, and VR/AR converge.
Beyond broad-based deep tech firms, these specialized investors have emerged as powerful players in their respective domains.
Gaming technology increasingly overlaps with broader deep tech applications, from real-time 3D simulation to immersive experiences.
Sector-focused investors like Konvoy bring both capital and invaluable industry connections that generalist firms cannot match.
Conclusion
Want More Insights on Venture Capital?
Explore the Venture Insiders blog to help you secure the capital your startup needs.
