You probably already know that Chicago is a major hotspot for innovation and investment.
Like New York and Denver, venture capital firms in Chicago are actively investing in areas such as technology, healthcare, fintech, and consumer goods.
This article will highlight the best venture capital firms in Chicago, covering their investment strategies, notable portfolio companies, and what they can offer to your startup or career.
Are you ready to explore the investment scene in the Windy City?
7 Best Venture Capital Firms in Chicago
If you’re an entrepreneur on the hunt for funding, an investor looking for some attractive opportunities, or just curious about the venture capital ecosystem, this is the top for you.
These are the top 7 venture capital firms in Chicago that definitely deserve a place on your radar.
1. Hyde Park Venture Partners
Founded in 2011, Hyde Park Venture Partners is an early-stage venture capital firm that focuses on high-growth technology startups.
What sets them apart as one of the best venture capital firms in Chicago is their exclusivity.
They only invest in companies rooted in the mid-continent, a region that includes the Midwest, along with Toronto and Atlanta.
If your company is based in this area and boasts an outstanding founding team with significant growth potential, and is looking to raise its first or second round of funding, then Hyde Park Venture Partners is the right fit for you.
Some of the companies in their portfolio are ShipBob, Zengines, G2, and Dentologie.
2. ARCH Venture Partners
ARCH Venture Partners is one of the leading venture capital firms in Chicago.
They focus on supporting life science innovations that help prevent, detect, and cure diseases.
ARCH invests in companies across various sectors within the healthcare industry, including Pharmaceuticals, Biotechnology, Genetics, Medical Artificial Intelligence, Nanotechnology, Medical Devices, and more.
Since they started in 1986, ARCH Venture Partners has funded 460 companies and achieved 102 successful exits.
They fund in Series A, Series B, and Series C rounds.
3. Chicago Ventures
Chicago Ventures focuses on investing in well-managed seed-stage technology companies based in Chicago and the Greater Midwest.
The fund typically makes initial investments ranging from $250,000 to $1 million in each selected company.
Among the standout companies in their portfolio are AeroPay, a promising player in the fintech sector, G2 from the marketing field, and HealthJoy, which operates in healthcare.
As one of the top venture capital firms in Chicago, this partner is ready to support founders with a straightforward vision that demonstrates clear value.
4. Bridge Investments
Bridge Investments is recognized as one of the leading venture capital firms in Chicago, renowned for its culture of creativity and collaboration.
They specialize in supporting early-stage startups within the consumer brand and SaaS industries.
The founders, who are entrepreneurs too, know how to team up and help guide everyone through all the important steps on their journey.
The portfolio of Bridge Investments boasts notable companies such as Casetext, Simple Mills, Caraway, and Haku.
5. Jump Capital
Jump Capital is one of the top venture capital firms in Chicago that invests in technology-enabled companies.
Their portfolio includes notable companies like Osano, Avia, and Kinetiq.
Jump Capital invests in businesses at different stages, including Early-Stage, Late-Stage, and Seed rounds. This approach allows them to support a variety of companies.
Founders working on fintech, application software, and infrastructure software can find a helpful partner in Jump Capital.
6. Konvoy
Konvoy is a thesis-driven venture capital firm based in Denver and Chicago.
Focused on the cutting-edge platforms and technologies at the forefront of gaming, they provide strategic advice and support for future capital-raising efforts.
As one of the top venture capital firms in Chicago, Konvoy has carved out a niche for itself in the gaming market.
Their portfolio includes companies such as Nerd Street, Ixana, Canopus Networks, Battle Road, and others.
7. New Stack Ventures
New Stack Ventures stands out as one of the leading venture capital firms in Chicago, actively investing in industries such as fintech, SaaS, proptech, and healthcare.
They make investments ranging from $500,000 to $1.5 million.
This firm targets early-stage companies with strong potential that are located outside traditional tech hubs like Silicon Valley or New York.
Notable portfolio companies include Draftbit, Clora, and Curv.
Conclusion
In 2025, the top 7 venture capital firms in Chicago are ready to support startups in different areas, including fintech, healthcare, supply chain, and SaaS.
These firms are looking for innovative founders ready to make a significant impact within their industries.
Depending on your field, any of these partners might be a great choice.
Which one stands out to you the most? Are you ready to reach out to them?
